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Albuterol is longer acting than isoproterenol in most patients because it is not a substrate for the cellular uptake processes for catecholamines nor for metabolism by catechol-O-methyl transferaseInsteadthe drug is conjugatively metabolized to albuterol 4O-sulfate.
To spray the productfirmly press once on the canister against the mouthpiece as shown in Figure 4Keep breathing in deeply.
Additional adverse reactionsreported in less than two percent of the patients in the COMBIVENT Inhalation Aerosol treatment group include edemafatiguehypertensiondizzinessnervousnessparesthesiatremordysphoniainsomniadiarrheadry mouthdyspepsiavomitingarrhythmiapalpitationtachycardiaarthralgiaanginaincreased sputumtaste perversionand urinary tract infection/dysuria.
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