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Hypersensitivity to doxazosin, other quinazolines, or any other ingredient in cardura.
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If you stop taking Cardura for any reasonask your doctor before you start taking it againYou may need a dose adjustment.
Patients with hepatic impairmentAs with any drug wholly metabolised by the liverCardura XL should be administered with caution to patients with evidence of impaired hepatic functionsee section 4.4 and 5.2
As there are no adequate and well-controlled studies in pregnant womenthe safety of Cardura XL during pregnancy has not yet been establishedAccordinglyduring pregnancyCardura XL should be used only whenin the opinion of the physicianthe potential benefit outweighs the potential risk.
Allergic reactionsincluding urticariarashangioedemapruritusand respiratory symptoms may occur.
Initiation of TherapyIn relation with the alpha-blocking properties of doxazosinpatients may experience postural hypotension evidenced by dizziness and weaknessor rarely loss of consciousnesssyncopeparticularly with the commencement of therapysee section 4.2Thereforeit is prudent medical practice to monitor blood pressure on initiation of therapy to minimise the potential for postural effects.
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3 ml sec in maximum flow rate were seen with cardura xl tablets in studies 1 and 2, compared to 0.