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A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation.
This communication will focus on the prevalenceetiologypathophysiologyand the current treatment options for PEMore specificallya novel selective serotonin reuptake inhibitorSSRIdapoxetinewill be evaluated for its pharmacokineticsefficacyand safety record in light of available preclinical and clinical data.
There are three basic mechanisms involved in normal ante-grade ejaculationemissionexpulsionand orgasmand each of these components possesses separate neural pathwaysEjaculatory dysfunction can result from disruption of any point in this cascade of eventsSeveral recent studies have clarified some aspects of the physiology of ejaculationEmissionwhich begins with closure of the bladder neck to prevent retrograde flow of seminal fluid and sperm into the bladderrefers to the bupron sr online game deposition of seminal fluid and sperm from the distal epididymisvas deferensseminal vesiclesand prostate into the posterior urethraWitt and Grantmyre 1993
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